Cargando…
Cellular Cullin RING Ubiquitin Ligases: Druggable Host Dependency Factors of Cytomegaloviruses
Human cytomegalovirus (HCMV) is a ubiquitous betaherpesvirus that frequently causes morbidity and mortality in individuals with insufficient immunity, such as transplant recipients, AIDS patients, and congenitally infected newborns. Several antiviral drugs are approved to treat HCMV infections. Howe...
Autores principales: | Becker, Tanja, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479302/ https://www.ncbi.nlm.nih.gov/pubmed/30986950 http://dx.doi.org/10.3390/ijms20071636 |
Ejemplares similares
-
Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus
por: Flores-Martínez, Yulia Alejandra, et al.
Publicado: (2021) -
Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2017) -
Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication
por: Eilbrecht, Mareike, et al.
Publicado: (2020) -
A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx
por: Landsberg, Christine D., et al.
Publicado: (2018) -
Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2023)