Cargando…
Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats
Diabetes mellitus (DM) has significant effects on cardiac calcium (Ca(2+)) and sodium (Na(+)) regulation. Clinical studies have shown that empagliflozin (Jardiance™) has cardiovascular benefits, however the mechanisms have not been fully elucidated. This study aimed to investigate whether empagliflo...
Autores principales: | Lee, Ting-I, Chen, Yao-Chang, Lin, Yung-Kuo, Chung, Cheng-Chih, Lu, Yen-Yu, Kao, Yu-Hsun, Chen, Yi-Jen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479313/ https://www.ncbi.nlm.nih.gov/pubmed/30987285 http://dx.doi.org/10.3390/ijms20071680 |
Ejemplares similares
-
Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis
por: Chung, Cheng-Chih, et al.
Publicado: (2023) -
Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes
por: Huang, Shih-Yu, et al.
Publicado: (2016) -
Calcium dysregulation increases right ventricular outflow tract arrhythmogenesis in rabbit model of chronic kidney disease
por: Huang, Shih‐Yu, et al.
Publicado: (2021) -
Redox and Activation of Protein Kinase A Dysregulates Calcium Homeostasis in Pulmonary Vein Cardiomyocytes of Chronic Kidney Disease
por: Huang, Shih‐Yu, et al.
Publicado: (2017) -
Fibroblast Growth Factor 1 Reduces Pulmonary Vein and Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis
por: Lu, Yen-Yu, et al.
Publicado: (2022)