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Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress
Ring finger protein 146 (RNF146) is an E3 ubiquitin ligase whose activity prevents poly (ADP-ribose) polymerase 1 (PARP1)-dependent neurodegeneration in Parkinson’s disease (PD). Previously, we reported that rhododendrin is a chemical inducer that increases RNF146 expression. However, the molecular...
Autores principales: | Kim, Hyojung, Park, Jisoo, Leem, HyunHee, Cho, MyoungLae, Yoon, Jin-Ha, Maeng, Han-Joo, Lee, Yunjong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479468/ https://www.ncbi.nlm.nih.gov/pubmed/30974833 http://dx.doi.org/10.3390/ijms20071772 |
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