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A Molecular Dynamics Approach to Explore the Intramolecular Signal Transduction of PPAR-α
Dynamics and functions of the peroxisome proliferator-activated receptor (PPAR)-α are modulated by the types of ligands that bind to the orthosteric sites. While several X-ray crystal structures of PPAR-α have been determined in their agonist-bound forms, detailed structural information in their apo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479491/ https://www.ncbi.nlm.nih.gov/pubmed/30987171 http://dx.doi.org/10.3390/ijms20071666 |