Cargando…

Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells

Although human pluripotent stem cells (hPSCs) can theoretically differentiate into any cell type, their ability to produce hematopoietic cells is highly variable from one cell line to another. The underlying mechanisms of this heterogeneity are not clearly understood. Here, using a whole miRNome ana...

Descripción completa

Detalles Bibliográficos
Autores principales:	Flamant, Stéphane, Chomel, Jean-Claude, Desterke, Christophe, Féraud, Olivier, Gobbo, Emilie, Mitjavila-Garcia, Maria-Teresa, Foudi, Adlen, Griscelli, Frank, Turhan, Ali G., Bennaceur-Griscelli, Annelise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479521/ https://www.ncbi.nlm.nih.gov/pubmed/30965622 http://dx.doi.org/10.3390/ijms20071737

Ejemplares similares

iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma
por: Hwang, Jin Wook, et al.
Publicado: (2019)

Detection of Hematopoietic Stem Cell Transcriptome in Human Fetal Kidneys and Kidney Organoids Derived From Human Induced Pluripotent Stem Cells
por: Hwang, Jin Wook, et al.
Publicado: (2021)

EGR1 dysregulation defines an inflammatory and leukemic program in cell trajectory of human-aged hematopoietic stem cells (HSC)
por: Desterke, Christophe, et al.
Publicado: (2021)

PPARγ Cistrome Repression during Activation of Lung Monocyte-Macrophages in Severe COVID-19
por: Desterke, Christophe, et al.
Publicado: (2020)

HLA-dependent heterogeneity and macrophage immunoproteasome activation during lung COVID-19 disease
por: Desterke, Christophe, et al.
Publicado: (2021)

Genomic landscape analyses of reprogrammed cells using integrative and non-integrative methods reveal variable cancer-associated alterations
por: Griscelli, Frank, et al.
Publicado: (2019)

Evidence of Antitumor and Antimetastatic Potential of Induced Pluripotent Stem Cell-Based Vaccines in Cancer Immunotherapy
por: Kishi, Masae, et al.
Publicado: (2021)

Morphological Analysis of Human Induced Pluripotent Stem Cells During Induced Differentiation and Reverse Programming
por: Courtot, Anne-Marie, et al.
Publicado: (2014)

Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid leukemia (CML)
por: Gentil, Melanie, et al.
Publicado: (2018)

Donor Dependent Variations in Hematopoietic Differentiation among Embryonic and Induced Pluripotent Stem Cell Lines
por: Féraud, Olivier, et al.
Publicado: (2016)

Modeling Blast Crisis Using Mutagenized Chronic Myeloid Leukemia-Derived Induced Pluripotent Stem Cells (iPSCs)
por: Imeri, Jusuf, et al.
Publicado: (2023)

Molecular investigation of adequate sources of mesenchymal stem cells for cell therapy of COVID‐19‐associated organ failure
por: Desterke, Christophe, et al.
Publicado: (2020)

Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding
por: Desterke, Christophe, et al.
Publicado: (2020)

iPSC-Derived Organoids as Therapeutic Models in Regenerative Medicine and Oncology
por: Turhan, Ali G., et al.
Publicado: (2021)

ENOX2 NADH Oxidase: A BCR-ABL1-Dependent Cell Surface and Secreted Redox Protein in Chronic Myeloid Leukemia
por: Baykal, Seda, et al.
Publicado: (2023)

Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
por: Congras, Annabelle, et al.
Publicado: (2016)

Genomic instability of human embryonic stem cell lines using different passaging culture methods
por: Tosca, Lucie, et al.
Publicado: (2015)

iPSC-Derived Hereditary Breast Cancer Model Reveals the BRCA1-Deleted Tumor Niche as a New Culprit in Disease Progression
por: Portier, Lucie, et al.
Publicado: (2021)

Corrigendum: Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
por: Congras, Annabelle, et al.
Publicado: (2018)

Deciphering Potential Molecular Signatures to Differentiate Acute Myeloid Leukemia (AML) with BCR::ABL1 from Chronic Myeloid Leukemia (CML) in Blast Crisis
por: Boucher, Lara, et al.
Publicado: (2023)

Identification of Spectral Modifications Occurring during Reprogramming of Somatic Cells
por: Sandt, Christophe, et al.
Publicado: (2012)

Modeling Global Genomic Instability in Chronic Myeloid Leukemia (CML) Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs)
por: Telliam, Gladys, et al.
Publicado: (2023)

The HOXB4 Homeoprotein Promotes the Ex Vivo Enrichment of Functional Human Embryonic Stem Cell-Derived NK Cells
por: Larbi, Aniya, et al.
Publicado: (2012)

Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors
por: Aggoune, Djamel, et al.
Publicado: (2014)

Case report: Long-term voluntary Tyrosine Kinase Inhibitor (TKI) discontinuation in chronic myeloid leukemia (CML): Molecular evidence of an immune surveillance
por: Imeri, Jusuf, et al.
Publicado: (2023)

Patient-Derived iPSCs Reveal Evidence of Telomere Instability and DNA Repair Deficiency in Coats Plus Syndrome
por: Oudrhiri, Noufissa, et al.
Publicado: (2022)

Clinically silent indolent T‐cell leukemia
por: Janot, Clément, et al.
Publicado: (2018)

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance
por: Ozmadenci, Duygu, et al.
Publicado: (2015)

A mesenchymal glioma stem cell profile is related to clinical outcome
por: Balbous, A, et al.
Publicado: (2014)

Leukemic stem cell persistence in chronic myeloid leukemia patients in deep molecular response induced by tyrosine kinase inhibitors and the impact of therapy discontinuation
por: Chomel, Jean Claude, et al.
Publicado: (2016)

Defining Hematopoietic Stem and Progenitor Cell Turnover by Analysis of Histone 2B-GFP Dilution
por: Foudi, Adlen, et al.
Publicado: (2008)

CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress
por: Zhang, Yanyan, et al.
Publicado: (2016)

THE DISTRIBUTION OF LARGE DIVIDING LYMPH NODE CELLS IN SYNGENEIC RECIPIENT RATS AFTER INTRAVENOUS INJECTION
por: Griscelli, Claude, et al.
Publicado: (1969)

BMAL1 knockdown triggers different colon carcinoma cell fates by altering the delicate equilibrium between AKT/mTOR and P53/P21 pathways
por: Zhang, Yuan, et al.
Publicado: (2020)

CABLES1 Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners
por: He, Liang, et al.
Publicado: (2019)

Sex and Circadian Timing Modulate Oxaliplatin Hematological and Hematopoietic Toxicities
por: Dulong, Sandrine, et al.
Publicado: (2022)

Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice
por: Hadadi, Eva, et al.
Publicado: (2020)

BMAL1 Knockdown Leans Epithelial–Mesenchymal Balance toward Epithelial Properties and Decreases the Chemoresistance of Colon Carcinoma Cells
por: Zhang, Yuan, et al.
Publicado: (2021)

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy
por: Chomel, Jean-Claude, et al.
Publicado: (2011)

Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206
por: Liang, Yu, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m85sp99omq9q04m37m98lq6c43