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Silybin Modulates Collagen Turnover in an In Vitro Model of NASH

Silybin has been proposed as a treatment for nonalcoholic steatohepatitis (NASH). In this study, we assessed the effect of Silybin in a well-established in vitro coculture model of early-stage NASH. LX2 and Huh7 cells were exposed to free fatty acid (FFA) and Silybin as mono- or coculture (SCC). Cel...

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Detalles Bibliográficos
Autores principales: Anfuso, Beatrice, Giraudi, Pablo J., Tiribelli, Claudio, Rosso, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479571/
https://www.ncbi.nlm.nih.gov/pubmed/30986937
http://dx.doi.org/10.3390/molecules24071280

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