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Ion Channels Involved in Substance P-Mediated Nociception and Antinociception

Substance P (SP), an 11-amino-acid neuropeptide, has long been considered an effector of pain. However, accumulating studies have proposed a paradoxical role of SP in anti-nociception. Here, we review studies of SP-mediated nociception and anti-nociception in terms of peptide features, SP-modulated...

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Detalles Bibliográficos
Autores principales: Chang, Chu-Ting, Jiang, Bo-Yang, Chen, Chih-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479580/
https://www.ncbi.nlm.nih.gov/pubmed/30935032
http://dx.doi.org/10.3390/ijms20071596