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Ion Channels Involved in Substance P-Mediated Nociception and Antinociception
Substance P (SP), an 11-amino-acid neuropeptide, has long been considered an effector of pain. However, accumulating studies have proposed a paradoxical role of SP in anti-nociception. Here, we review studies of SP-mediated nociception and anti-nociception in terms of peptide features, SP-modulated...
Autores principales: | Chang, Chu-Ting, Jiang, Bo-Yang, Chen, Chih-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479580/ https://www.ncbi.nlm.nih.gov/pubmed/30935032 http://dx.doi.org/10.3390/ijms20071596 |
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