Structure-Based Virtual Screening and In Vitro Evaluation of New Trypanosoma cruzi Cruzain Inhibitors

Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per year in the Americas. Current medical therapy for CD has low efficacy in the chronic phase of the disease and serious adverse effects; therefore, it is necessary to search for new pharmacological treatments. In this...

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Detalles Bibliográficos
Autores principales: Herrera-Mayorga, Verónica, Lara-Ramírez, Edgar E., Chacón-Vargas, Karla F., Aguirre-Alvarado, Charmina, Rodríguez-Páez, Lorena, Alcántara-Farfán, Verónica, Cordero-Martínez, Joaquín, Nogueda-Torres, Benjamín, Reyes-Espinosa, Francisco, Bocanegra-García, Virgilio, Rivera, Gildardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479639/
https://www.ncbi.nlm.nih.gov/pubmed/30970549
http://dx.doi.org/10.3390/ijms20071742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479639/
https://www.ncbi.nlm.nih.gov/pubmed/30970549
http://dx.doi.org/10.3390/ijms20071742

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