Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing

The Nrf2 signal transduction pathway plays a major role in adaptive responses to oxidative stress and in maintaining adaptive homeostasis, yet Nrf2 signaling undergoes a significant age-dependent decline that is still poorly understood. We used mouse embryonic fibroblasts (MEFs) cultured under hyper...

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Detalles Bibliográficos
Autores principales: Pomatto, Laura C.D., Sun, Patrick Y., Yu, Kelsi, Gullapalli, Sandhyarani, Bwiza, Conscience P., Sisliyan, Christina, Wong, Sarah, Zhang, Hongqiao, Forman, Henry Jay, Oliver, Peter L., Davies, Kay E., Davies, Kelvin J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479762/
https://www.ncbi.nlm.nih.gov/pubmed/31022673
http://dx.doi.org/10.1016/j.redox.2019.101194

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