Modulation of the IL-6-Signaling Pathway in Liver Cells by miRNAs Targeting gp130, JAK1, and/or STAT3

Interleukin-6 (IL-6)-type cytokines share the common receptor glycoprotein 130 (gp130), which activates a signaling cascade involving Janus kinases (JAKs) and signal transducer and activator of transcription (STAT) transcription factors. IL-6 and/or its signaling pathway is often deregulated in dise...

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Detalles Bibliográficos
Autores principales: Servais, Florence A., Kirchmeyer, Mélanie, Hamdorf, Matthias, Minoungou, Nadège W.E., Rose-John, Stefan, Kreis, Stephanie, Haan, Claude, Behrmann, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479786/
https://www.ncbi.nlm.nih.gov/pubmed/31026677
http://dx.doi.org/10.1016/j.omtn.2019.03.007

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