The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most aggressive types of cancer and lacks effective therapeutic approaches. Most HCC develops in the setting of chronic liver injury, hepatic inflammation, and fibrosis. Hepatic stellate cells (HSCs) and cancer-associated fibroblasts (CAFs) are key player...

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Detalles Bibliográficos
Autores principales: Baglieri, Jacopo, Brenner, David A., Kisseleva, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479943/
https://www.ncbi.nlm.nih.gov/pubmed/30959975
http://dx.doi.org/10.3390/ijms20071723

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