Cargando…

The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases

Activated protein C (APC) is a vitamin-K dependent plasma serine protease, which functions as a natural anticoagulant to downregulate thrombin generation in the clotting cascade. APC also modulates cellular homeostasis by exhibiting potent cytoprotective and anti-inflammatory signaling activities. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Di, Giri, Hemant, Li, Ji, Rezaie, Alireza R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479968/
https://www.ncbi.nlm.nih.gov/pubmed/30974752
http://dx.doi.org/10.3390/ijms20071762