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The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases

Activated protein C (APC) is a vitamin-K dependent plasma serine protease, which functions as a natural anticoagulant to downregulate thrombin generation in the clotting cascade. APC also modulates cellular homeostasis by exhibiting potent cytoprotective and anti-inflammatory signaling activities. T...

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Detalles Bibliográficos
Autores principales:	Ren, Di, Giri, Hemant, Li, Ji, Rezaie, Alireza R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479968/ https://www.ncbi.nlm.nih.gov/pubmed/30974752 http://dx.doi.org/10.3390/ijms20071762

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