Cargando…
Intracellular Delivery of Biologically-Active Fungal Metabolite Gliotoxin Using Magnetic Nanoparticles
Gliotoxin (GT), a secondary metabolite produced by Aspergillus molds, has been proposed as a potential anti-tumor agent. Here we have developed a nanoparticle approach to enhance delivery of GT in tumor cells and establish a basis for its potential use as therapeutical drug. GT bound to magnetic nan...
Autores principales: | Comas, Laura, Polo, Esther, Domingo, M Pilar, Hernández, Yulán, Arias, Maykel, Esteban, Patricia, Martínez-Lostao, Luis, Pardo, Julián, Martínez de la Fuente, Jesús, Gálvez, Eva M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480141/ https://www.ncbi.nlm.nih.gov/pubmed/30987007 http://dx.doi.org/10.3390/ma12071092 |
Ejemplares similares
-
Preparations for Invasion: Modulation of Host Lung Immunity During Pulmonary Aspergillosis by Gliotoxin and Other Fungal Secondary Metabolites
por: Arias, Maykel, et al.
Publicado: (2018) -
Integration of In Silico and In Vitro Analysis of Gliotoxin Production Reveals a Narrow Range of Producing Fungal Species
por: Redrado, Sergio, et al.
Publicado: (2022) -
In Vitro and In Vivo Antibacterial Activity of Gliotoxin Alone and in Combination with Antibiotics against Staphylococcus aureus
por: Esteban, Patricia, et al.
Publicado: (2021) -
Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis
por: Vidal-García, Matxalen, et al.
Publicado: (2018) -
The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB
Publicado: (1996)