Cargando…

HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem Cell-Derived Neurons

Recent studies show that histone deacetylase 6 (HDAC6) has important roles in the human brain, especially in the context of a number of nervous system disorders. Animal models of neurodevelopmental, neurodegenerative, and neuropsychiatric disorders show that HDAC6 modulates important biological proc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iaconelli, Jonathan, Xuan, Lucius, Karmacharya, Rakesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480207/ https://www.ncbi.nlm.nih.gov/pubmed/30935091 http://dx.doi.org/10.3390/ijms20071605

Ejemplares similares

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells
por: Iaconelli, Jonathan, et al.
Publicado: (2014)

Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia
por: Kathuria, Annie, et al.
Publicado: (2023)

HDAC1 Regulates Neuronal Differentiation
por: Nieto-Estevez, Vanesa, et al.
Publicado: (2022)

HDAC6 in Diseases of Cognition and of Neurons
por: LoPresti, Patrizia
Publicado: (2020)

HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons
por: Chen, Sigeng, et al.
Publicado: (2010)

Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons
por: Nazir, Faisal Hayat, et al.
Publicado: (2018)

Histone Deacetylase (HDAC) Inhibitors - Emerging Roles in Neuronal Memory, Learning, Synaptic Plasticity and Neural Regeneration
por: Ahmad Ganai, Shabir, et al.
Publicado: (2016)

HDAC6 and Miro1: Another interaction causing trouble in neurons
por: Van Den Bosch, Ludo
Publicado: (2019)

S193. EX VIVO SIGNATURE OF PSYCHOSIS AND TREATMENT RESPONSE IN PATIENT-DERIVED NEURONS
por: Karmacharya, Rakesh, et al.
Publicado: (2018)

In Vitro Differentiated Human Stem Cell-Derived Neurons Reproduce Synaptic Synchronicity Arising during Neurodevelopment
por: Rosa, Filip, et al.
Publicado: (2020)

Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons
por: Xu, Jian-Yi, et al.
Publicado: (2010)

Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides
por: Frankowski, Harald, et al.
Publicado: (2021)

Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition
por: Bertels, Zachariah, et al.
Publicado: (2021)

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
por: Dujardin, Simon, et al.
Publicado: (2014)

Modulation of Neuronal Signal Transduction and Memory Formation by Synaptic Zinc
por: Sindreu, Carlos, et al.
Publicado: (2011)

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture
por: Graham, Laura C., et al.
Publicado: (2017)

Editorial: Role of Protein Palmitoylation in Synaptic Plasticity and Neuronal Differentiation
por: Yoshii, Akira, et al.
Publicado: (2020)

Inhibition of HDAC6 activity protects dopaminergic neurons from alpha-synuclein toxicity
por: Francelle, Laetitia, et al.
Publicado: (2020)

Synaptically-Competent Neurons Derived from Canine Embryonic Stem Cells by Lineage Selection with EGF and Noggin
por: Wilcox, Jared T., et al.
Publicado: (2011)

HDAC6 regulates dental mesenchymal stem cells and osteoclast differentiation
por: Wang, Yi, et al.
Publicado: (2018)

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
por: Guo, Wenting, et al.
Publicado: (2017)

Neuronal Activity Changes the Number of Neurons That Are Synaptically Connected to OPCs
por: Moura, Daniela, et al.
Publicado: (2023)

Neuronal Differentiation of Human Mesenchymal Stem Cells Using Exosomes Derived from Differentiating Neuronal Cells
por: Takeda, Yuji S., et al.
Publicado: (2015)

Acute modulation of synaptic plasticity of pyramidal neurons by activin in adult hippocampus
por: Hasegawa, Yoshitaka, et al.
Publicado: (2014)

The epitranscriptome in modulating spatiotemporal RNA translation in neuronal post-synaptic function
por: Hussain, Shobbir, et al.
Publicado: (2015)

STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons
por: Yang, Juan, et al.
Publicado: (2020)

Cerebellar modulation of synaptic input to freezing-related neurons in the periaqueductal gray
por: Vaaga, Christopher E, et al.
Publicado: (2020)

Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory
por: Lu, Yujiao, et al.
Publicado: (2019)

Terahertz exposure enhances neuronal synaptic transmission and oligodendrocyte differentiation in vitro
por: Zhao, Xianghui, et al.
Publicado: (2021)

Modulating the Electrical and Mechanical Microenvironment to Guide Neuronal Stem Cell Differentiation
por: Oh, Byeongtaek, et al.
Publicado: (2021)

HDAC6 Inhibitor Blocks Amyloid Beta-Induced Impairment of Mitochondrial Transport in Hippocampal Neurons
por: Kim, Chaeyoung, et al.
Publicado: (2012)

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
por: McSweeney, Danny, et al.
Publicado: (2022)

Visualizing the Synaptic and Cellular Ultrastructure in Neurons Differentiated from Human Induced Neural Stem Cells—An Optimized Protocol
por: Capetian, Philipp, et al.
Publicado: (2020)

Orexin Modulation of VTA Dopamine Neuron Activity: Relevance to Schizophrenia
por: Perez, Stephanie M, et al.
Publicado: (2021)

The dopamine neuron synaptic map in the striatum
por: Chuhma, Nao, et al.
Publicado: (2023)

Adult-born neurons modify excitatory synaptic transmission to existing neurons
por: Adlaf, Elena W, et al.
Publicado: (2017)

Neuronal inhibition and synaptic plasticity of basal ganglia neurons in Parkinson's disease
por: Milosevic, Luka, et al.
Publicado: (2018)

Biologically Relevant Dynamical Behaviors Realized in an Ultra-Compact Neuron Model
por: Stoliar, Pablo, et al.
Publicado: (2020)

Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure
por: Iijima, Yoko, et al.
Publicado: (2016)

Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons
por: Munguba, Hermany, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f5542fmv2948udg6q09mrrm28i