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Untargeted Metabolomics Study of the In Vitro Anti-Hepatoma Effect of Saikosaponin d in Combination with NRP-1 Knockdown

Saikosaponin d (SSd) is one of the main active ingredients in Radix Bupleuri. In our study, network pharmacology databases and metabolomics were used in combination to explore the new targets and reveal the in-depth mechanism of SSd. A total of 35 potential targets were chosen through database searc...

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Detalles Bibliográficos
Autores principales: Lv, Yingtong, Hou, Xiaoying, Zhang, Qianqian, Li, Ruiting, Xu, Lei, Chen, Yadong, Tian, Yuan, Sun, Rong, Zhang, Zunjian, Xu, Fengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480384/
https://www.ncbi.nlm.nih.gov/pubmed/30978940
http://dx.doi.org/10.3390/molecules24071423