Concerted Catalysis by Nanocellulose and Proline in Organocatalytic Michael Additions

Cellulose nanofibers (CNFs) have recently attracted much attention as catalysts in various reactions. Organocatalysts have emerged as sustainable alternatives to metal-based catalysts in green organic synthesis, with concerted systems containing CNFs that are expected to provide next-generation cata...

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Detalles Bibliográficos
Autores principales: Ranaivoarimanana, Naliharifetra Jessica, Kanomata, Kyohei, Kitaoka, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480416/
https://www.ncbi.nlm.nih.gov/pubmed/30934821
http://dx.doi.org/10.3390/molecules24071231
Descripción
Sumario:Cellulose nanofibers (CNFs) have recently attracted much attention as catalysts in various reactions. Organocatalysts have emerged as sustainable alternatives to metal-based catalysts in green organic synthesis, with concerted systems containing CNFs that are expected to provide next-generation catalysis. Herein, for the first time, we report that a representative organocatalyst comprising an unexpected combination of 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO)-oxidized CNFs and proline shows significantly enhanced catalytic activity in an asymmetric Michael addition.

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