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Efficient gene transfer into T lymphocytes by fiber-modified human adenovirus 5

BACKGROUND: The gene transduction efficiency of adenovirus to hematopoietic cells, especially T lymphocytes, is needed to be improved. The purpose of this study is to improve the transduction efficiency of T lymphocytes by using fiber-modified human adenovirus 5 (HAdV-5) vectors. RESULTS: Four fiber...

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Detalles Bibliográficos
Autores principales: Lv, Yun, Xiao, Feng-Jun, Wang, Yi, Zou, Xiao-Hui, Wang, Hua, Wang, Hai-Yan, Wang, Li-Sheng, Lu, Zhuo-Zhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480437/
https://www.ncbi.nlm.nih.gov/pubmed/31014302
http://dx.doi.org/10.1186/s12896-019-0514-x

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