IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats

(1) Background: Chemokine-like factor 1 (CKLF1) is a chemokine with potential to be a target for stroke therapy. Compound IMM-H004 is a novel coumarin derivative screened from a CKLF1/C-C chemokine receptor type 4 (CCR4) system and has been reported to improve cerebral ischemia/reperfusion injury. T...

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Detalles Bibliográficos
Autores principales: Ai, Qidi, Chen, Chen, Chu, Shifeng, Luo, Yun, Zhang, Zhao, Zhang, Shuai, Yang, Pengfei, Gao, Yan, Zhang, Xiaoling, Chen, Naihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480569/
https://www.ncbi.nlm.nih.gov/pubmed/30987181
http://dx.doi.org/10.3390/ijms20071661

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