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New Dammarane-Type Saponins from Gynostemma pentaphyllum
Six new dammarane-type saponins, gypenosides CP1-6 (1–6), along with 19 known compounds 7–25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferati...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480664/ https://www.ncbi.nlm.nih.gov/pubmed/30965662 http://dx.doi.org/10.3390/molecules24071375 |
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| author | Chen, Po-Yen Chang, Chih-Chao Huang, Hui-Chi Zhang, Li-Jie Liaw, Chia-Ching Lin, Yu-Chi Nguyen, Nham-Linh Vo, Thanh-Hoa Cheng, Yung-Yi Morris-Natschke, Susan L. Lee, Kuo-Hsiung Kuo, Yao-Haur |
| author_facet | Chen, Po-Yen Chang, Chih-Chao Huang, Hui-Chi Zhang, Li-Jie Liaw, Chia-Ching Lin, Yu-Chi Nguyen, Nham-Linh Vo, Thanh-Hoa Cheng, Yung-Yi Morris-Natschke, Susan L. Lee, Kuo-Hsiung Kuo, Yao-Haur |
| author_sort | Chen, Po-Yen |
| collection | PubMed |
| description | Six new dammarane-type saponins, gypenosides CP1-6 (1–6), along with 19 known compounds 7–25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2). |
| format | Online Article Text |
| id | pubmed-6480664 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-64806642019-04-30 New Dammarane-Type Saponins from Gynostemma pentaphyllum Chen, Po-Yen Chang, Chih-Chao Huang, Hui-Chi Zhang, Li-Jie Liaw, Chia-Ching Lin, Yu-Chi Nguyen, Nham-Linh Vo, Thanh-Hoa Cheng, Yung-Yi Morris-Natschke, Susan L. Lee, Kuo-Hsiung Kuo, Yao-Haur Molecules Article Six new dammarane-type saponins, gypenosides CP1-6 (1–6), along with 19 known compounds 7–25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2). MDPI 2019-04-08 /pmc/articles/PMC6480664/ /pubmed/30965662 http://dx.doi.org/10.3390/molecules24071375 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Chen, Po-Yen Chang, Chih-Chao Huang, Hui-Chi Zhang, Li-Jie Liaw, Chia-Ching Lin, Yu-Chi Nguyen, Nham-Linh Vo, Thanh-Hoa Cheng, Yung-Yi Morris-Natschke, Susan L. Lee, Kuo-Hsiung Kuo, Yao-Haur New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title | New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title_full | New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title_fullStr | New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title_full_unstemmed | New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title_short | New Dammarane-Type Saponins from Gynostemma pentaphyllum |
| title_sort | new dammarane-type saponins from gynostemma pentaphyllum |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480664/ https://www.ncbi.nlm.nih.gov/pubmed/30965662 http://dx.doi.org/10.3390/molecules24071375 |
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