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Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler’s Murine Encephalomyelitis

Theiler’s murine encephalomyelitis (TME) represents a versatile animal model for studying the pathogenesis of demyelinating diseases such as multiple sclerosis. Hallmarks of TME are demyelination, astrogliosis, as well as inflammation. Previous studies showed that matrix metalloproteinase 12 knockou...

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Detalles Bibliográficos
Autores principales: Hansmann, Florian, Zhang, Ning, Herder, Vanessa, Leitzen, Eva, Baumgärtner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480673/
https://www.ncbi.nlm.nih.gov/pubmed/30959793
http://dx.doi.org/10.3390/ijms20071702