Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes

In rodent skeletal muscle, acyl-coenzyme A (CoA) synthetase 5 (ACSL-5) is suggested to localize to the mitochondria but its precise function in human skeletal muscle is unknown. The purpose of these studies was to define the role of ACSL-5 in mitochondrial fatty acid metabolism and the potential eff...

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Detalles Bibliográficos
Autores principales: Kwak, Hyo-Bum, Woodlief, Tracey L., Green, Thomas D., Cox, Julie H., Hickner, Robert C., Neufer, P. Darrell, Cortright, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480682/
https://www.ncbi.nlm.nih.gov/pubmed/30935113
http://dx.doi.org/10.3390/ijerph16071157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480682/
https://www.ncbi.nlm.nih.gov/pubmed/30935113
http://dx.doi.org/10.3390/ijerph16071157

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