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Pneumonitis resulting from radiation and immune checkpoint blockade illustrates characteristic clinical, radiologic and circulating biomarker features

BACKGROUND: Pneumonitis is a potential consequence of both lung-directed radiation and immune checkpoint blockade (ICB), particularly treatment with PD-1/PD-L1 inhibitors. Significant morbidity and mortality can result, and severe pneumonitis attributed to ICB precludes continued therapy. Thus, disc...

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Detalles Bibliográficos
Autores principales: Schoenfeld, Jonathan D., Nishino, Mizuki, Severgnini, Mariano, Manos, Michael, Mak, Raymond H., Hodi, F. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480873/
https://www.ncbi.nlm.nih.gov/pubmed/31014385
http://dx.doi.org/10.1186/s40425-019-0583-3