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TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression

BACKGROUND: Genome-wide association studies have identified over 160 loci that are associated with coronary artery disease. As with other complex human diseases, risk in coronary disease loci is determined primarily by altered expression of the causal gene, due to variation in binding of transcripti...

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Detalles Bibliográficos
Autores principales:	Zhao, Quanyi, Wirka, Robert, Nguyen, Trieu, Nagao, Manabu, Cheng, Paul, Miller, Clint L., Kim, Juyong Brian, Pjanic, Milos, Quertermous, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480881/ https://www.ncbi.nlm.nih.gov/pubmed/31014396 http://dx.doi.org/10.1186/s13073-019-0635-9

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