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Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

BACKGROUND: Prothrombin complex concentrate (PCC) is widely used to reverse the action of direct oral anticoagulants (DOACs) in accordance with current guidelines and because of a lack of specific reversal agents. Indications, clinical characteristics and patient outcomes of patients might differ in...

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Detalles Bibliográficos
Autores principales: Müller, Martin, Eastline, Jonathan, Nagler, Michael, Exadaktylos, Aristomenis K., Sauter, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480883/
https://www.ncbi.nlm.nih.gov/pubmed/31014373
http://dx.doi.org/10.1186/s13049-019-0625-3