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The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells

BACKGROUND: To evaluate the cross-talk between BRCA1-IRIS (IRIS)-overexpressing (IRISOE) TNBC cells and tumor-resident mesenchymal stem cells (MSCs) that triggers the aggressiveness or elimination of IRISOE TNBC tumors. METHODS: We analyzed the effect of silencing or inactivating IRIS on the bi-dire...

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Detalles Bibliográficos
Autores principales:	Ryan, Daniel, Paul, Bibbin T., Koziol, Jim, ElShamy, Wael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480921/ https://www.ncbi.nlm.nih.gov/pubmed/31014367 http://dx.doi.org/10.1186/s13058-019-1131-2

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