Cargando…

Genetic Modification of Mucor circinelloides to Construct Stearidonic Acid Producing Cell Factory

Stearidonic acid (SDA; 18:4, n-3) is the delta 15-desaturase product of gamma linolenic acid (GLA; 18:3, n-6) and delta 6-desaturase product of alpha linolenic acid (ALA; 18:3, n-3). Construction of engineered oleaginous microbes have been attracting significant interest in producing SDA because of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Md. Ahsanul Kabir, Yang, Junhuan, Hussain, Syed Ammar, Zhang, Huaiyuan, Garre, Victoriano, Song, Yuanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480972/ https://www.ncbi.nlm.nih.gov/pubmed/30987311 http://dx.doi.org/10.3390/ijms20071683

Ejemplares similares

Construction of DGLA producing cell factory by genetic modification of Mucor circinelloides
por: Khan, Md. Ahsanul Kabir, et al.
Publicado: (2019)

Engineering of Fatty Acid Synthases (FASs) to Boost the Production of Medium-Chain Fatty Acids (MCFAs) in Mucor circinelloides
por: Hussain, Syed Ammar, et al.
Publicado: (2019)

Increased Accumulation of Medium-Chain Fatty Acids by Dynamic Degradation of Long-Chain Fatty Acids in Mucor circinelloides
por: Hussain, Syed Ammar, et al.
Publicado: (2020)

Antioxidants Potential of the Filamentous Fungi (Mucor circinelloides)
por: Hameed, Ahsan, et al.
Publicado: (2017)

Improved γ-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases
por: Zhang, Yao, et al.
Publicado: (2017)

Genetic Modification of Mucor circinelloides for Canthaxanthin Production by Heterologous Expression of β-carotene Ketolase Gene
por: Naz, Tahira, et al.
Publicado: (2021)

Role of Snf-β in lipid accumulation in the high lipid‐producing fungus Mucor circinelloides WJ11
por: Nosheen, Shaista, et al.
Publicado: (2021)

Comparison of Biochemical Activities between High and Low Lipid-Producing Strains of Mucor circinelloides: An Explanation for the High Oleaginicity of Strain WJ11
por: Tang, Xin, et al.
Publicado: (2015)

Role of Cytosolic Malic Enzyme in Oleaginicity of High-Lipid-Producing Fungal Strain Mucor circinelloides WJ11
por: Fazili, Abu Bakr Ahmad, et al.
Publicado: (2022)

Heterologous Expression of Two Malate Transporters From an Oleaginous Fungus Mucor circinelloides Improved the Lipid Accumulation in Mucor lusitanicus
por: Wang, Xiuwen, et al.
Publicado: (2021)

(13)C metabolic flux analysis on roles of malate transporter in lipid accumulation of Mucor circinelloides
por: Wang, Lu, et al.
Publicado: (2019)

Understanding Mucor circinelloides pathogenesis by comparative genomics and phenotypical studies
por: López-Fernández, Loida, et al.
Publicado: (2018)

Comparative Analysis of β-Carotene Production by Mucor circinelloides Strains CBS 277.49 and WJ11 under Light and Dark Conditions
por: Naz, Tahira, et al.
Publicado: (2020)

Homologous and Heterologous Expression of Delta(12)-Desaturase in Mucor circinelloides Enhanced the Production of Linolenic Acid
por: Yang, Junhuan, et al.
Publicado: (2022)

Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination Pathway
por: Pérez-Arques, Carlos, et al.
Publicado: (2019)

The RNAi machinery controls distinct responses to environmental signals in the basal fungus Mucor circinelloides
por: Nicolás, Francisco E, et al.
Publicado: (2015)

Mucor circinelloides: a model organism for oleaginous fungi and its potential applications in bioactive lipid production
por: Fazili, Abu Bakr Ahmad, et al.
Publicado: (2022)

Molecular Mechanism of Citrate Efflux by the Mitochondrial Citrate Transporter CT in Filamentous Fungus Mucor circinelloides WJ11
por: Yang, Wu, et al.
Publicado: (2021)

Identification and Functional Characterization of Adenosine Deaminase in Mucor circinelloides: A Novel Potential Regulator of Nitrogen Utilization and Lipid Biosynthesis
por: Li, Shaoqi, et al.
Publicado: (2022)

Overexpression of the Mitochondrial Malic Enzyme Genes (malC and malD) Improved the Lipid Accumulation in Mucor circinelloides WJ11
por: Fazili, Abu Bakr Ahmad, et al.
Publicado: (2022)

Tricarboxylate Citrate Transporter of an Oleaginous Fungus Mucor circinelloides WJ11: From Function to Structure and Role in Lipid Production
por: Yang, Wu, et al.
Publicado: (2021)

Simultaneous overexpression of ∆6-, ∆12- and ∆9-desaturases enhanced the production of γ-linolenic acid in Mucor circinelloides WJ11
por: Wang, Xiuwen, et al.
Publicado: (2022)

A new regulatory mechanism controlling carotenogenesis in the fungus Mucor circinelloides as a target to generate β-carotene over-producing strains by genetic engineering
por: Zhang, Yingtong, et al.
Publicado: (2016)

Generation of A Mucor circinelloides Reporter Strain—A Promising New Tool to Study Antifungal Drug Efficacy and Mucormycosis
por: Binder, Ulrike, et al.
Publicado: (2018)

Investigating the Effect of Alcohol Dehydrogenase Gene Knockout on Lipid Accumulation in Mucor circinelloides WJ11
por: Shah, Aabid Manzoor, et al.
Publicado: (2022)

Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides
por: Li, Charles H., et al.
Publicado: (2011)

Proteomics analysis of high lipid-producing strain Mucor circinelloides WJ11: an explanation for the mechanism of lipid accumulation at the proteomic level
por: Tang, Xin, et al.
Publicado: (2016)

Enhanced lipid production by addition of malic acid in fermentation of recombinant Mucor circinelloides Mc-MT-2
por: Zhang, Yao, et al.
Publicado: (2021)

Bioconversion of cheese whey permeate into fungal oil by Mucor circinelloides
por: Chan, Lauryn G., et al.
Publicado: (2018)

Antimycotic Activity of Some Medicinal Plants against Mucor circinelloides
por: Jangid, Renu, et al.
Publicado: (2022)

Development of a plasmid free CRISPR-Cas9 system for the genetic modification of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2017)

Metabolic traits specific for lipid-overproducing strain of Mucor circinelloides WJ11 identified by genome-scale modeling approach
por: Isarankura Na Ayudhya, Nattapat, et al.
Publicado: (2019)

Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides
por: Garcia, Alexis, et al.
Publicado: (2017)

Production, Purification, and Characterization of Polygalacturonase from Mucor circinelloides ITCC 6025
por: Thakur, Akhilesh, et al.
Publicado: (2010)

Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2014)

Old Yellow Enzyme homologues in Mucor circinelloides: expression profile and biotransformation
por: Romagnolo, Alice, et al.
Publicado: (2017)

A new species concept for the clinically relevant Mucor circinelloides complex
por: Wagner, L., et al.
Publicado: (2019)

Complete Genome Sequence of a High Lipid-Producing Strain of Mucor circinelloides WJ11 and Comparative Genome Analysis with a Low Lipid-Producing Strain CBS 277.49
por: Tang, Xin, et al.
Publicado: (2015)

Cloning and expression of an active aspartic proteinase from Mucor circinelloides in Pichia pastoris
por: Gama Salgado, Jose Antonio, et al.
Publicado: (2013)

Detection of the Dimorphic Phases of Mucor circinelloides in Blood Cultures from an Immunosuppressed Female
por: Arroyo, Miguel A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5cc70jfq036tnbccbplrequhku