A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature

We are reporting a case of a 54-year-old transgender female with a history of breast augmentation with bilateral silicone implants. Seventeen years later, she presented with an enlarging right breast mass. Pathology confirmed breast implant–associated anaplastic large cell lymphoma (Ann Arbor Stage...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Naba, Sindhu, Kunal, Bakst, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480983/
https://www.ncbi.nlm.nih.gov/pubmed/31010324
http://dx.doi.org/10.1177/2324709619842192
_version_ 1783413690762002432
author Ali, Naba
Sindhu, Kunal
Bakst, Richard L.
author_facet Ali, Naba
Sindhu, Kunal
Bakst, Richard L.
author_sort Ali, Naba
collection PubMed
description We are reporting a case of a 54-year-old transgender female with a history of breast augmentation with bilateral silicone implants. Seventeen years later, she presented with an enlarging right breast mass. Pathology confirmed breast implant–associated anaplastic large cell lymphoma (Ann Arbor Stage IIE, TNM Stage III BIA-ALCL). The patient underwent bilateral capsulectomy, sentinel lymph node biopsy with adjuvant CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy, and radiotherapy to the right chest, axilla, and supraclavicular lymph nodes. BIA-ALCL is a rare entity, especially in transgender females. We report this case and a review of the literature in this report.
format Online
Article
Text
id pubmed-6480983
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-64809832019-04-30 A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature Ali, Naba Sindhu, Kunal Bakst, Richard L. J Investig Med High Impact Case Rep Case Report We are reporting a case of a 54-year-old transgender female with a history of breast augmentation with bilateral silicone implants. Seventeen years later, she presented with an enlarging right breast mass. Pathology confirmed breast implant–associated anaplastic large cell lymphoma (Ann Arbor Stage IIE, TNM Stage III BIA-ALCL). The patient underwent bilateral capsulectomy, sentinel lymph node biopsy with adjuvant CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy, and radiotherapy to the right chest, axilla, and supraclavicular lymph nodes. BIA-ALCL is a rare entity, especially in transgender females. We report this case and a review of the literature in this report. SAGE Publications 2019-04-22 /pmc/articles/PMC6480983/ /pubmed/31010324 http://dx.doi.org/10.1177/2324709619842192 Text en © 2019 American Federation for Medical Research http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Ali, Naba
Sindhu, Kunal
Bakst, Richard L.
A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title_full A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title_fullStr A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title_full_unstemmed A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title_short A Rare Case of a Transgender Female With Breast Implant–Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature
title_sort rare case of a transgender female with breast implant–associated anaplastic large cell lymphoma treated with radiotherapy and a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480983/
https://www.ncbi.nlm.nih.gov/pubmed/31010324
http://dx.doi.org/10.1177/2324709619842192
work_keys_str_mv AT alinaba ararecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature
AT sindhukunal ararecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature
AT bakstrichardl ararecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature
AT alinaba rarecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature
AT sindhukunal rarecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature
AT bakstrichardl rarecaseofatransgenderfemalewithbreastimplantassociatedanaplasticlargecelllymphomatreatedwithradiotherapyandareviewoftheliterature

Ejemplares similares