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Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice

Interleukin- (IL-) 35, a novel functional cytokine of regulatory T cells (Treg) comprised of the IL-12p35 subunit and the other subunit Epstein-Barr virus-induced gene 3 (EBI3), regulates the activity of CD4+ T cells and macrophages, thereby playing a critical role in inflammatory and autoimmune dis...

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Detalles Bibliográficos
Autores principales:	Huang, Ying, Hu, Haiying, Liu, Ling, Ye, Jing, Wang, Zhen, Que, Bin, Liu, Wenjing, Shi, Ying, Zeng, Tao, Shi, Lei, Ji, Qingwei, Chang, Chao, Lin, Yingzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481022/ https://www.ncbi.nlm.nih.gov/pubmed/31093011 http://dx.doi.org/10.1155/2019/3152040

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