Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis

A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3),...

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Autores principales: Lai, D., Dave, N., Raghavan, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481119/
https://www.ncbi.nlm.nih.gov/pubmed/31093390
http://dx.doi.org/10.1155/2019/8720837
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author Lai, D.
Dave, N.
Raghavan, R.
author_facet Lai, D.
Dave, N.
Raghavan, R.
author_sort Lai, D.
collection PubMed
description A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3), anti-nuclear and anti-histone antibodies. The clinical diagnosis was Drug-Induced ANCA Vasculitis (DIAV). Kidney histology, however, did not reveal crescents, but showed characteristic features of Alport's syndrome.
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spelling pubmed-64811192019-05-15 Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis Lai, D. Dave, N. Raghavan, R. Case Rep Nephrol Case Report A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3), anti-nuclear and anti-histone antibodies. The clinical diagnosis was Drug-Induced ANCA Vasculitis (DIAV). Kidney histology, however, did not reveal crescents, but showed characteristic features of Alport's syndrome. Hindawi 2019-04-10 /pmc/articles/PMC6481119/ /pubmed/31093390 http://dx.doi.org/10.1155/2019/8720837 Text en Copyright © 2019 D. Lai et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lai, D.
Dave, N.
Raghavan, R.
Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title_full Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title_fullStr Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title_full_unstemmed Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title_short Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
title_sort incidentally diagnosed alport syndrome in a patient with drug-induced vasculitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481119/
https://www.ncbi.nlm.nih.gov/pubmed/31093390
http://dx.doi.org/10.1155/2019/8720837
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