Cargando…

Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia

BACKGROUND: Jaundice in the neonate is one of the most common clinical problems. Globally, every year about 1.1 million babies develop it and the vast majority reside in sub-Saharan Africa and South Asia. Study on magnitude and local factors associated with neonatal jaundice is limited in Ethiopia....

Descripción completa

Detalles Bibliográficos
Autores principales: Lake, Eyasu A., Abera, Gerezgiher B., Azeze, Gedion A., Gebeyew, Natnaeal A., Demissie, Birhanu W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481120/
https://www.ncbi.nlm.nih.gov/pubmed/31093292
http://dx.doi.org/10.1155/2019/1054943
_version_ 1783413720160927744
author Lake, Eyasu A.
Abera, Gerezgiher B.
Azeze, Gedion A.
Gebeyew, Natnaeal A.
Demissie, Birhanu W.
author_facet Lake, Eyasu A.
Abera, Gerezgiher B.
Azeze, Gedion A.
Gebeyew, Natnaeal A.
Demissie, Birhanu W.
author_sort Lake, Eyasu A.
collection PubMed
description BACKGROUND: Jaundice in the neonate is one of the most common clinical problems. Globally, every year about 1.1 million babies develop it and the vast majority reside in sub-Saharan Africa and South Asia. Study on magnitude and local factors associated with neonatal jaundice is limited in Ethiopia. So this study was aimed at assessing magnitude and predictors of neonatal jaundice among neonates admitted to neonatal intensive care unit of public hospitals in Mekelle city, Northern Ethiopia. METHODS: Institution based cross-sectional study was conducted from February to April 2016 in neonatal intensive care unit of Mekelle city public hospitals. Systematic random sampling technique was used to select study participants. Data was collected by interviewing mothers through structured questionnaire and reviewing neonates' medical records using checklist. Multivariable binary logistic regression analyses were employed to identify factors associated with neonatal jaundice. RESULTS: A total of 209 neonates with their mothers were included. The proportion of neonatal jaundice was found to be 37.3%. Prolonged labor [AOR = 4.39; 95% CI (1.8-10.69)], being male [AOR = 3.7; 95% CI (1.54-8.87)], maternal “O” blood group [AOR = 5.05; 95% CI (1.53-16.72)], sepsis [AOR = 2.64; 95% CI (1.15-6.05)], and blood type incompatibility [AOR = 18.21; 95% CI (6.36-52.13)] were positively associated with neonatal jaundice while night time delivery [AOR 0.42; 95% CI (0.18-0.96)] showed negative association. CONCLUSION: The magnitude of neonatal jaundice among neonates was found to be high. Duration of labor, time of delivery, sexes of neonate, sepsis, maternal blood group, and blood type incompatibility were significantly associated with neonatal jaundice. Therefore, improving newborn care and timely intervention for neonates with ABO/Rh incompatibility are recommended.
format Online
Article
Text
id pubmed-6481120
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-64811202019-05-15 Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia Lake, Eyasu A. Abera, Gerezgiher B. Azeze, Gedion A. Gebeyew, Natnaeal A. Demissie, Birhanu W. Int J Pediatr Research Article BACKGROUND: Jaundice in the neonate is one of the most common clinical problems. Globally, every year about 1.1 million babies develop it and the vast majority reside in sub-Saharan Africa and South Asia. Study on magnitude and local factors associated with neonatal jaundice is limited in Ethiopia. So this study was aimed at assessing magnitude and predictors of neonatal jaundice among neonates admitted to neonatal intensive care unit of public hospitals in Mekelle city, Northern Ethiopia. METHODS: Institution based cross-sectional study was conducted from February to April 2016 in neonatal intensive care unit of Mekelle city public hospitals. Systematic random sampling technique was used to select study participants. Data was collected by interviewing mothers through structured questionnaire and reviewing neonates' medical records using checklist. Multivariable binary logistic regression analyses were employed to identify factors associated with neonatal jaundice. RESULTS: A total of 209 neonates with their mothers were included. The proportion of neonatal jaundice was found to be 37.3%. Prolonged labor [AOR = 4.39; 95% CI (1.8-10.69)], being male [AOR = 3.7; 95% CI (1.54-8.87)], maternal “O” blood group [AOR = 5.05; 95% CI (1.53-16.72)], sepsis [AOR = 2.64; 95% CI (1.15-6.05)], and blood type incompatibility [AOR = 18.21; 95% CI (6.36-52.13)] were positively associated with neonatal jaundice while night time delivery [AOR 0.42; 95% CI (0.18-0.96)] showed negative association. CONCLUSION: The magnitude of neonatal jaundice among neonates was found to be high. Duration of labor, time of delivery, sexes of neonate, sepsis, maternal blood group, and blood type incompatibility were significantly associated with neonatal jaundice. Therefore, improving newborn care and timely intervention for neonates with ABO/Rh incompatibility are recommended. Hindawi 2019-04-10 /pmc/articles/PMC6481120/ /pubmed/31093292 http://dx.doi.org/10.1155/2019/1054943 Text en Copyright © 2019 Eyasu A. Lake et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lake, Eyasu A.
Abera, Gerezgiher B.
Azeze, Gedion A.
Gebeyew, Natnaeal A.
Demissie, Birhanu W.
Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title_full Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title_fullStr Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title_full_unstemmed Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title_short Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
title_sort magnitude of neonatal jaundice and its associated factor in neonatal intensive care units of mekelle city public hospitals, northern ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481120/
https://www.ncbi.nlm.nih.gov/pubmed/31093292
http://dx.doi.org/10.1155/2019/1054943
work_keys_str_mv AT lakeeyasua magnitudeofneonataljaundiceanditsassociatedfactorinneonatalintensivecareunitsofmekellecitypublichospitalsnorthernethiopia
AT aberagerezgiherb magnitudeofneonataljaundiceanditsassociatedfactorinneonatalintensivecareunitsofmekellecitypublichospitalsnorthernethiopia
AT azezegediona magnitudeofneonataljaundiceanditsassociatedfactorinneonatalintensivecareunitsofmekellecitypublichospitalsnorthernethiopia
AT gebeyewnatnaeala magnitudeofneonataljaundiceanditsassociatedfactorinneonatalintensivecareunitsofmekellecitypublichospitalsnorthernethiopia
AT demissiebirhanuw magnitudeofneonataljaundiceanditsassociatedfactorinneonatalintensivecareunitsofmekellecitypublichospitalsnorthernethiopia