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Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations

Inference of tumor and edema areas from brain magnetic resonance imaging (MRI) data remains challenging owing to the complex structure of brain tumors, blurred boundaries, and external factors such as noise. To alleviate noise sensitivity and improve the stability of segmentation, an effective hybri...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Shen, Xuanjing, Cheng, Hang, Qian, Qingji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481128/
https://www.ncbi.nlm.nih.gov/pubmed/31093268
http://dx.doi.org/10.1155/2019/7305832
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author Zhang, Chong
Shen, Xuanjing
Cheng, Hang
Qian, Qingji
author_facet Zhang, Chong
Shen, Xuanjing
Cheng, Hang
Qian, Qingji
author_sort Zhang, Chong
collection PubMed
description Inference of tumor and edema areas from brain magnetic resonance imaging (MRI) data remains challenging owing to the complex structure of brain tumors, blurred boundaries, and external factors such as noise. To alleviate noise sensitivity and improve the stability of segmentation, an effective hybrid clustering algorithm combined with morphological operations is proposed for segmenting brain tumors in this paper. The main contributions of the paper are as follows: firstly, adaptive Wiener filtering is utilized for denoising, and morphological operations are used for removing nonbrain tissue, effectively reducing the method's sensitivity to noise. Secondly, K-means++ clustering is combined with the Gaussian kernel-based fuzzy C-means algorithm to segment images. This clustering not only improves the algorithm's stability, but also reduces the sensitivity of clustering parameters. Finally, the extracted tumor images are postprocessed using morphological operations and median filtering to obtain accurate representations of brain tumors. In addition, the proposed algorithm was compared with other current segmentation algorithms. The results show that the proposed algorithm performs better in terms of accuracy, sensitivity, specificity, and recall.
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spelling pubmed-64811282019-05-15 Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations Zhang, Chong Shen, Xuanjing Cheng, Hang Qian, Qingji Int J Biomed Imaging Research Article Inference of tumor and edema areas from brain magnetic resonance imaging (MRI) data remains challenging owing to the complex structure of brain tumors, blurred boundaries, and external factors such as noise. To alleviate noise sensitivity and improve the stability of segmentation, an effective hybrid clustering algorithm combined with morphological operations is proposed for segmenting brain tumors in this paper. The main contributions of the paper are as follows: firstly, adaptive Wiener filtering is utilized for denoising, and morphological operations are used for removing nonbrain tissue, effectively reducing the method's sensitivity to noise. Secondly, K-means++ clustering is combined with the Gaussian kernel-based fuzzy C-means algorithm to segment images. This clustering not only improves the algorithm's stability, but also reduces the sensitivity of clustering parameters. Finally, the extracted tumor images are postprocessed using morphological operations and median filtering to obtain accurate representations of brain tumors. In addition, the proposed algorithm was compared with other current segmentation algorithms. The results show that the proposed algorithm performs better in terms of accuracy, sensitivity, specificity, and recall. Hindawi 2019-04-09 /pmc/articles/PMC6481128/ /pubmed/31093268 http://dx.doi.org/10.1155/2019/7305832 Text en Copyright © 2019 Chong Zhang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Chong
Shen, Xuanjing
Cheng, Hang
Qian, Qingji
Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title_full Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title_fullStr Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title_full_unstemmed Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title_short Brain Tumor Segmentation Based on Hybrid Clustering and Morphological Operations
title_sort brain tumor segmentation based on hybrid clustering and morphological operations
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481128/
https://www.ncbi.nlm.nih.gov/pubmed/31093268
http://dx.doi.org/10.1155/2019/7305832
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