Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus

A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel oral...

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Detalles Bibliográficos
Autores principales: Rahbani, Abdallah, Adwane, Grace, Jomaa, Najo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481131/
https://www.ncbi.nlm.nih.gov/pubmed/31093391
http://dx.doi.org/10.1155/2019/8537815
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author Rahbani, Abdallah
Adwane, Grace
Jomaa, Najo
author_facet Rahbani, Abdallah
Adwane, Grace
Jomaa, Najo
author_sort Rahbani, Abdallah
collection PubMed
description A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel orally via nasogastric tube and the dose was rapidly increased to 8 mg after 12 hours with cessation of clinical and electrical seizures. Other antiepileptic drugs were tapered progressively with an excellent clinical outcome.
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spelling pubmed-64811312019-05-15 Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus Rahbani, Abdallah Adwane, Grace Jomaa, Najo Case Rep Neurol Med Case Report A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel orally via nasogastric tube and the dose was rapidly increased to 8 mg after 12 hours with cessation of clinical and electrical seizures. Other antiepileptic drugs were tapered progressively with an excellent clinical outcome. Hindawi 2019-04-09 /pmc/articles/PMC6481131/ /pubmed/31093391 http://dx.doi.org/10.1155/2019/8537815 Text en Copyright © 2019 Abdallah Rahbani et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rahbani, Abdallah
Adwane, Grace
Jomaa, Najo
Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title_full Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title_fullStr Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title_full_unstemmed Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title_short Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
title_sort oral perampanel for the treatment of super-refractory status epilepticus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481131/
https://www.ncbi.nlm.nih.gov/pubmed/31093391
http://dx.doi.org/10.1155/2019/8537815
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