Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis

Allele-specific expression (ASE) is found in approximately 20-30% of human genes. During tumorigenesis, ASE changes due to somatic alterations that change the regulatory landscape. In colorectal cancer (CRC), many chromosomes show frequent gains or losses while homozygosity of chromosome 7 is rare....

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Detalles Bibliográficos
Autores principales: Boot, Arnoud, Oosting, Jan, Doorn, Saskia, Ouahoud, Sarah, Ventayol Garcia, Marina, Ruano, Dina, Morreau, Hans, van Wezel, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481143/
https://www.ncbi.nlm.nih.gov/pubmed/31093489
http://dx.doi.org/10.1155/2019/1287671

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