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Comparison of Risk of Osteoporotic Fracture in Denosumab vs Alendronate Treatment Within 3 Years of Initiation

IMPORTANCE: Head-to-head randomized clinical trials showed greater efficacy of denosumab vs alendronate in improving bone mineral density. Although there is an association of changes in bone mineral density with reductions in fracture risk, the magnitude of the association is not well established. O...

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Detalles Bibliográficos
Autores principales: Pedersen, Alma B., Heide-Jørgensen, Uffe, Sørensen, Henrik T., Prieto-Alhambra, Daniel, Ehrenstein, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481596/
https://www.ncbi.nlm.nih.gov/pubmed/31002319
http://dx.doi.org/10.1001/jamanetworkopen.2019.2416