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Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2

Interleukin (IL)-2 is a pleiotropic cytokine that is necessary to prevent chronic inflammation in the gastrointestinal tract(1–4). The protective effects of IL-2 involve the generation, maintenance and function of regulatory T cells (Tregs)(4–8), and low-dose IL-2 has emerged as a potential therapeu...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Chu, Coco, Teng, Fei, Bessman, Nicholas J., Goc, Jeremy, Santosa, Endi K., Putzel, Gregory G., Kabata, Hiroki, Kelsen, Judith R., Baldassano, Robert N., Shah, Manish A., Sockolow, Robbyn E., Vivier, Eric, Eberl, Gérard, Smith, Kendall A., Sonnenberg, Gregory F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481643/
https://www.ncbi.nlm.nih.gov/pubmed/30944470
http://dx.doi.org/10.1038/s41586-019-1082-x