Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation

The differentiation of self-renewing progenitor cells requires not only the regulation of lineage- and developmental stage–specific genes but also the coordinated adaptation of housekeeping functions from a metabolically active, proliferative state toward quiescence. How metabolic and cell-cycle sta...

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Detalles Bibliográficos
Autores principales: Ferreirós-Vidal, Isabel, Carroll, Thomas, Zhang, Tianyi, Lagani, Vincenzo, Ramirez, Ricardo N., Ing-Simmons, Elizabeth, Gómez-Valadés, Alicia G., Cooper, Lee, Liang, Ziwei, Papoutsoglou, Georgios, Dharmalingam, Gopuraja, Guo, Ya, Tarazona, Sonia, Fernandes, Sunjay J., Noori, Peri, Silberberg, Gilad, Fisher, Amanda G., Tsamardinos, Ioannis, Mortazavi, Ali, Lenhard, Boris, Conesa, Ana, Tegner, Jesper, Merkenschlager, Matthias, Gomez-Cabrero, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481923/
https://www.ncbi.nlm.nih.gov/pubmed/30978178
http://dx.doi.org/10.1371/journal.pbio.2006506

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