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Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice
The circumventricular organs (CVOs) in the central nervous system (CNS) lack a vascular blood-brain barrier (BBB), creating communication sites for sensory or secretory neurons, involved in body homeostasis. Wnt/β-catenin signaling is essential for BBB development and maintenance in endothelial cell...
Autores principales: | Benz, Fabienne, Wichitnaowarat, Viraya, Lehmann, Martin, Germano, Raoul FV, Mihova, Diana, Macas, Jadranka, Adams, Ralf H, Taketo, M Mark, Plate, Karl-Heinz, Guérit, Sylvaine, Vanhollebeke, Benoit, Liebner, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481993/ https://www.ncbi.nlm.nih.gov/pubmed/30932814 http://dx.doi.org/10.7554/eLife.43818 |
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