Cargando…

Atomic structure of the translation regulatory protein NS1 of bluetongue virus

Bluetongue virus (BTV) non-structural protein 1 (NS1) regulates viral protein synthesis and exists as tubular and non-tubular forms in infected cells but how tubules assemble and how protein synthesis is regulated are unknown. Here, we report near-atomic resolution structures of two NS1 tubular form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kerviel, Adeline, Ge, Peng, Lai, Mason, Jih, Jonathan, Boyce, Mark, Zhang, Xing, Zhou, Z. Hong, Roy, Polly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482088/ https://www.ncbi.nlm.nih.gov/pubmed/30778144 http://dx.doi.org/10.1038/s41564-019-0369-x

Ejemplares similares

Differential Localization of Structural and Non-Structural Proteins during the Bluetongue Virus Replication Cycle
por: Mohl, Bjorn-Patrick, et al.
Publicado: (2020)

A Calcium Sensor Discovered in Bluetongue Virus Nonstructural Protein 2 Is Critical for Virus Replication
por: Rahman, Shah Kamranur, et al.
Publicado: (2020)

The Interaction of Bluetongue Virus VP6 and Genomic RNA Is Essential for Genome Packaging
por: Sung, Po-Yu, et al.
Publicado: (2019)

Bluetongue virus RNA binding protein NS2 is a modulator of viral replication and assembly
por: Kar, Alak Kanti, et al.
Publicado: (2007)

Bluetongue Virus Capsid Assembly and Maturation
por: Mohl, Bjorn-Patrick, et al.
Publicado: (2014)

Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis
por: Boyce, Mark, et al.
Publicado: (2012)

Multiple Routes of Bluetongue Virus Egress
por: Labadie, Thomas, et al.
Publicado: (2020)

Bluetongue Virus Nonstructural Protein NS3/NS3a Is Not Essential for Virus Replication
por: van Gennip, René G. P., et al.
Publicado: (2014)

Mapping the pH Sensors Critical for Host Cell Entry by a Complex Nonenveloped Virus
por: Wu, Weining, et al.
Publicado: (2019)

Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate
por: Stewart, Meredith E, et al.
Publicado: (2010)

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus
por: Bhattacharya, Bishnupriya, et al.
Publicado: (2013)

Structural constraints in the packaging of bluetongue virus genomic segments
por: Burkhardt, Christiane, et al.
Publicado: (2014)

Role of Lipids on Entry and Exit of Bluetongue Virus, a Complex Non-Enveloped Virus
por: Bhattacharya, Bishnupriya, et al.
Publicado: (2010)

Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence
por: Ratinier, Maxime, et al.
Publicado: (2016)

Comparative Virus-Host Protein Interactions of the Bluetongue Virus NS4 Virulence Factor
por: Fablet, Aurore, et al.
Publicado: (2022)

Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus
por: Sung, Po-Yu, et al.
Publicado: (2014)

Hsp90 Chaperones Bluetongue Virus Proteins and Prevents Proteasomal Degradation
por: Mohl, Bjorn-Patrick, et al.
Publicado: (2019)

Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis
por: Feenstra, Femke, et al.
Publicado: (2015)

Sialic Acid Binding Sites in VP2 of Bluetongue Virus and Their Use during Virus Entry
por: Wu, Weining, et al.
Publicado: (2022)

Influence of Cellular Trafficking Pathway on Bluetongue Virus Infection in Ovine Cells
por: Bhattacharya, Bishnupriya, et al.
Publicado: (2015)

Identification of four novel group-specific bluetongue virus NS3 protein B-cell epitopes
por: Qin, Zhang, et al.
Publicado: (2015)

Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress
por: Bhattacharya, Bishnupriya, et al.
Publicado: (2007)

Entry of Bluetongue Virus Capsid Requires the Late Endosome-specific Lipid Lysobisphosphatidic Acid
por: Patel, Avnish, et al.
Publicado: (2016)

Bluetongue Virus VP1 Polymerase Activity In Vitro: Template Dependency, Dinucleotide Priming and Cap Dependency
por: Matsuo, Eiko, et al.
Publicado: (2011)

Pathogenicity study in sheep using reverse-genetics-based reassortant bluetongue viruses
por: Celma, Cristina C., et al.
Publicado: (2014)

Cellular Casein Kinase 2 and Protein Phosphatase 2A Modulate Replication Site Assembly of Bluetongue Virus
por: Mohl, Bjorn-Patrick, et al.
Publicado: (2016)

Bluetongue Virus Nonstructural Protein 3 Orchestrates Virus Maturation and Drives Non-Lytic Egress via Two Polybasic Motifs
por: Labadie, Thomas, et al.
Publicado: (2019)

Interaction between a Unique Minor Protein and a Major Capsid Protein of Bluetongue Virus Controls Virus Infectivity
por: Matsuo, Eiko, et al.
Publicado: (2018)

Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge
por: Lulla, Valeria, et al.
Publicado: (2017)

Entry-competent-replication-abortive African horse sickness virus strains elicit robust immunity in ponies against all serotypes
por: Sullivan, Edward, et al.
Publicado: (2021)

Structure-based identification of functional residues in the nucleoside-2′-O-methylase domain of Bluetongue virus VP4 capping enzyme
por: Stewart, Meredith E., et al.
Publicado: (2015)

Experimental bluetongue virus superinfection in calves previously immunized with bluetongue virus serotype 8
por: Martinelle, Ludovic, et al.
Publicado: (2016)

Structure based modification of Bluetongue virus helicase protein VP6 to produce a viable VP6-truncated BTV
por: Matsuo, Eiko, et al.
Publicado: (2014)

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines
por: Celma, Cristina C., et al.
Publicado: (2016)

Characterization of Protection Afforded by a Bivalent Virus-Like Particle Vaccine against Bluetongue Virus Serotypes 1 and 4 in Sheep
por: Pérez de Diego, Ana Cristina, et al.
Publicado: (2011)

Implications of a conserved region of bluetongue virus protein VP2 in cross-neutralisation of bluetongue virus serotypes
por: Jyothi, Shiva J., et al.
Publicado: (2020)

PCR-based reverse genetics strategy for bluetongue virus recovery
por: Xu, Qingyuan, et al.
Publicado: (2019)

The Combined Expression of the Nonstructural Protein NS1 and the N-Terminal Half of NS2 (NS2(1-180)) by ChAdOx1 and MVA Confers Protection against Clinical Disease in Sheep upon Bluetongue Virus Challenge
por: Utrilla-Trigo, Sergio, et al.
Publicado: (2022)

Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia
por: Sana, Kalthoum, et al.
Publicado: (2022)

The Bluetongue Disabled Infectious Single Animal (DISA) Vaccine Platform Based on Deletion NS3/NS3a Protein Is Safe and Protective in Cattle and Enables DIVA
por: van Rijn, Piet A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_re1r03pi5732u0of2mrc92of0m