Cargando…

OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances cell-state reprogramming towards epithelial lineages

Mesenchymal-to-epithelial transition (MET) is an important step in cell reprogramming from fibroblasts (a cell type frequently used for this purpose) to various epithelial cell types. However, the mechanism underlying MET induction in fibroblasts remains to be understood. The present study aimed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Kazuhide, Liu, Ye, Noguchi, Shuhei, Murray, Madeleine, Chang, Jen-Chien, Kishima, Mami, Nishimura, Hajime, Hashimoto, Kosuke, Minoda, Aki, Suzuki, Harukazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482152/ https://www.ncbi.nlm.nih.gov/pubmed/31019211 http://dx.doi.org/10.1038/s41598-019-43021-z

Ejemplares similares

OVOL guides the epithelial-hybrid-mesenchymal transition
por: Jia, Dongya, et al.
Publicado: (2015)

Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer
por: Roca, Hernan, et al.
Publicado: (2013)

OVOL2 sustains postnatal thymic epithelial cell identity
por: Zhong, Xue, et al.
Publicado: (2023)

Combinatorial perturbation analysis reveals divergent regulations of mesenchymal genes during epithelial-to-mesenchymal transition
por: Watanabe, Kazuhide, et al.
Publicado: (2019)

A bioinformatics approach reveals novel interactions of the OVOL transcription factors in the regulation of epithelial – mesenchymal cell reprogramming and cancer progression
por: Roca, Hernan, et al.
Publicado: (2014)

An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal States
por: Hong, Tian, et al.
Publicado: (2015)

OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates
por: Kagawa, Harunobu, et al.
Publicado: (2019)

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma
por: Liu, Jijun, et al.
Publicado: (2018)

Prediction of transcription factors associated with DNA demethylation during human cellular development
por: Miyajima, Yurina, et al.
Publicado: (2022)

Expression of Ovol2 is related to epithelial characteristics and shows a favorable clinical outcome in hepatocellular carcinoma
por: Fu, Hui, et al.
Publicado: (2016)

OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma
por: Qi, Xue-Kang, et al.
Publicado: (2018)

Altered Epithelial-mesenchymal Plasticity as a Result of Ovol2 Deletion Minimally Impacts the Self-renewal of Adult Mammary Basal Epithelial Cells
por: Sun, Peng, et al.
Publicado: (2022)

Asymmetric Regulation of Peripheral Genes by Two Transcriptional Regulatory Networks
por: Li, Jing-Ru, et al.
Publicado: (2016)

OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis
por: Wu, Rong-Si, et al.
Publicado: (2017)

A screening system to identify transcription factors that induce binding site-directed DNA demethylation
por: Suzuki, Takahiro, et al.
Publicado: (2017)

OVOL2 in metastasis prevention in NPC
por: Song, Kyung-A, et al.
Publicado: (2018)

RUNX1 induces DNA replication independent of active DNA demethylation at SPI1 regulatory regions
por: Goyal, Shubham, et al.
Publicado: (2017)

Erratum to: RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions
por: Goyal, Shubham, et al.
Publicado: (2017)

Establishment of single-cell screening system for the rapid identification of transcriptional modulators involved in direct cell reprogramming
por: Shin, Jay W., et al.
Publicado: (2012)

From fibroblast cells to cardiomyocytes: direct lineage reprogramming
por: Yang, Lei
Publicado: (2011)

Dissecting the molecular trajectory of fibroblast reprogramming to chemically induced mammary epithelial cells
por: Qin, Liangshan, et al.
Publicado: (2023)

Epithelial lineage and transformation.
por: Hamilton, S. R.
Publicado: (1999)

Reprogramming of mouse fibroblasts into neural lineage cells using biomaterials
por: Kantawong, Fahsai, et al.
Publicado: (2018)

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes
por: de Jesus, Daniel S., et al.
Publicado: (2021)

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer
por: Zhang, Xiujuan, et al.
Publicado: (2022)

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics
por: Martinovich, Kelly M., et al.
Publicado: (2017)

Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway
por: Hirano, Akiko, et al.
Publicado: (2017)

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis
por: Tsuji, Gaku, et al.
Publicado: (2017)

Epigenetic reprogramming in the epithelial-to-mesenchymal transition
por: Hoang, Stephen, et al.
Publicado: (2012)

Comprehensive Analysis of the Expression, Prognosis, and Biological Significance of OVOLs in Breast Cancer
por: Chen, Jingsheng, et al.
Publicado: (2021)

GATA6 is predicted to regulate DNA methylation in an in vitro model of human hepatocyte differentiation
por: Suzuki, Takahiro, et al.
Publicado: (2022)

Directly reprogramming fibroblasts into adipogenic, neurogenic and hepatogenic differentiation lineages by defined factors
por: Wu, Wei, et al.
Publicado: (2017)

Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte
por: Shi, Xiaojie, et al.
Publicado: (2019)

Ovol2, a zinc finger transcription factor, is dispensable for spermatogenesis in mice
por: Zhang, Jin, et al.
Publicado: (2019)

“Pulsed Hypoxia” Gradually Reprograms Breast Cancer Fibroblasts into Pro-Tumorigenic Cells via Mesenchymal–Epithelial Transition
por: Nushtaeva, Anna, et al.
Publicado: (2023)

CeRNA Network Reveals the Circular RNA Characterization in Goat Ear Fibroblasts Reprogramming into Mammary Epithelial Cells
por: Sahito, Jam Zaheer Ahmed, et al.
Publicado: (2023)

Direct reprogramming of fibroblasts into diverse lineage cells by DNA demethylation followed by differentiating cultures
por: Yang, Dong-Wook, et al.
Publicado: (2020)

Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L
por: Breindel, Jerrica L., et al.
Publicado: (2017)

A dataset of definitive endoderm and hepatocyte differentiations from human induced pluripotent stem cells
por: Tanaka, Yuki, et al.
Publicado: (2023)

Treg regulation of the epithelial stem cell lineage
por: Cho, Inchul, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p51hej736eat7upcd0s7lhgtc0