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Nickel-catalyzed C–N bond activation: activated primary amines as alkylating reagents in reductive cross-coupling

Nickel-catalyzed reductive cross coupling of activated primary amines with aryl halides under mild reaction conditions has been achieved for the first time. Due to the avoidance of stoichiometric organometallic reagents and external bases, the scope regarding both coupling partners is broad. Thus, a...

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Detalles Bibliográficos
Autores principales: Yue, Huifeng, Zhu, Chen, Shen, Li, Geng, Qiuyang, Hock, Katharina J., Yuan, Tingting, Cavallo, Luigi, Rueping, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482441/
https://www.ncbi.nlm.nih.gov/pubmed/31057770
http://dx.doi.org/10.1039/c9sc00783k