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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

BACKGROUND/AIMS: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and degraded, precluding delivery to the cell surface [...

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Detalles Bibliográficos
Autores principales:	Sabirzhanova, Inna, Boinot, Clément, Guggino, William B., Cebotaru, Liudmila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482459/ https://www.ncbi.nlm.nih.gov/pubmed/30485852 http://dx.doi.org/10.1159/000495596

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