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Fixed-parameter tractable sampling for RNA design with multiple target structures
BACKGROUND: The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the need for costly wet-lab experiments. RESULTS: We devise a novel approa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482512/ https://www.ncbi.nlm.nih.gov/pubmed/31023239 http://dx.doi.org/10.1186/s12859-019-2784-7 |