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Unique RNA signature of different lesion types in the brain white matter in progressive multiple sclerosis

The heterogeneity of multiple sclerosis is reflected by dynamic changes of different lesion types in the brain white matter (WM). To identify potential drivers of this process, we RNA-sequenced 73 WM areas from patients with progressive MS (PMS) and 25 control WM. Lesion endophenotypes were describe...

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Detalles Bibliográficos
Autores principales: Elkjaer, Maria L., Frisch, Tobias, Reynolds, Richard, Kacprowski, Tim, Burton, Mark, Kruse, Torben A., Thomassen, Mads, Baumbach, Jan, Illes, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482546/
https://www.ncbi.nlm.nih.gov/pubmed/31023379
http://dx.doi.org/10.1186/s40478-019-0709-3