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Salinomycin triggers endoplasmic reticulum stress through ATP2A3 upregulation in PC-3 cells

BACKGROUND: Salinomycin is a monocarboxylic polyether antibiotic and is a potential chemotherapy drug. Our previous studies showed that salinomycin inhibited cell growth and targeted CSCs in prostate cancer. However, the precise target of salinomycin action is unclear. METHODS: In this work, we anal...

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Detalles Bibliográficos
Autores principales: Zhang, Yunsheng, Li, Fang, Liu, Luogen, Jiang, Hongtao, Hu, Hua, Du, Xiaobo, Ge, Xin, Cao, Jingsong, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482559/
https://www.ncbi.nlm.nih.gov/pubmed/31023247
http://dx.doi.org/10.1186/s12885-019-5590-8

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