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Emerging therapies for non-small cell lung cancer

Recent advances in the field of novel anticancer agents prolong patients’ survival and show a promising future. Tyrosine kinase inhibitors and immunotherapy for lung cancer are the two major areas undergoing rapid development. Although increasing novel anticancer agents were innovated, how to transl...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Leighl, Natasha B., Wu, Yi-Long, Zhong, Wen-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482588/
https://www.ncbi.nlm.nih.gov/pubmed/31023335
http://dx.doi.org/10.1186/s13045-019-0731-8
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author Zhang, Chao
Leighl, Natasha B.
Wu, Yi-Long
Zhong, Wen-Zhao
author_facet Zhang, Chao
Leighl, Natasha B.
Wu, Yi-Long
Zhong, Wen-Zhao
author_sort Zhang, Chao
collection PubMed
description Recent advances in the field of novel anticancer agents prolong patients’ survival and show a promising future. Tyrosine kinase inhibitors and immunotherapy for lung cancer are the two major areas undergoing rapid development. Although increasing novel anticancer agents were innovated, how to translate and optimize these novel agents into clinical practice remains to be explored. Besides, toxicities and availability of these drugs in specific regions should also be considered during clinical determination. Herein, we summarize emerging agents including tyrosine kinase inhibitors, checkpoint inhibitors, and other potential immunotherapy such as chimeric antigen receptor T cell for non-small cell lung cancer attempting to provide insights and perspectives of the future in anticancer treatment.
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spelling pubmed-64825882019-05-02 Emerging therapies for non-small cell lung cancer Zhang, Chao Leighl, Natasha B. Wu, Yi-Long Zhong, Wen-Zhao J Hematol Oncol Review Recent advances in the field of novel anticancer agents prolong patients’ survival and show a promising future. Tyrosine kinase inhibitors and immunotherapy for lung cancer are the two major areas undergoing rapid development. Although increasing novel anticancer agents were innovated, how to translate and optimize these novel agents into clinical practice remains to be explored. Besides, toxicities and availability of these drugs in specific regions should also be considered during clinical determination. Herein, we summarize emerging agents including tyrosine kinase inhibitors, checkpoint inhibitors, and other potential immunotherapy such as chimeric antigen receptor T cell for non-small cell lung cancer attempting to provide insights and perspectives of the future in anticancer treatment. BioMed Central 2019-04-25 /pmc/articles/PMC6482588/ /pubmed/31023335 http://dx.doi.org/10.1186/s13045-019-0731-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Zhang, Chao
Leighl, Natasha B.
Wu, Yi-Long
Zhong, Wen-Zhao
Emerging therapies for non-small cell lung cancer
title Emerging therapies for non-small cell lung cancer
title_full Emerging therapies for non-small cell lung cancer
title_fullStr Emerging therapies for non-small cell lung cancer
title_full_unstemmed Emerging therapies for non-small cell lung cancer
title_short Emerging therapies for non-small cell lung cancer
title_sort emerging therapies for non-small cell lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482588/
https://www.ncbi.nlm.nih.gov/pubmed/31023335
http://dx.doi.org/10.1186/s13045-019-0731-8
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