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The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

Human p300 is a transcriptional co-activator and a major acetyltransferase that acetylates histones and other proteins facilitating gene transcription. The activity of p300 relies on the fine-tuned interactome that involves a dozen p300 domains and hundreds of binding partners and links p300 to a wi...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Xue, Yongming, Shi, Jiejun, Ahn, JaeWoo, Mi, Wenyi, Ali, Muzaffar, Wang, Xiaolu, Klein, Brianna J., Wen, Hong, Li, Wei, Shi, Xiaobing, Kutateladze, Tatiana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482957/
https://www.ncbi.nlm.nih.gov/pubmed/30150647
http://dx.doi.org/10.1038/s41594-018-0114-9