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The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3
Human p300 is a transcriptional co-activator and a major acetyltransferase that acetylates histones and other proteins facilitating gene transcription. The activity of p300 relies on the fine-tuned interactome that involves a dozen p300 domains and hundreds of binding partners and links p300 to a wi...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482957/ https://www.ncbi.nlm.nih.gov/pubmed/30150647 http://dx.doi.org/10.1038/s41594-018-0114-9 |