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Disease Pathway Cut for Multi-Target drugs

BACKGROUND: Biomarker discovery studies have been moving the focus from a single target gene to a set of target genes. However, the number of target genes in a drug should be minimum to avoid drug side-effect or toxicity. But still, the set of target genes should effectively block all possible paths...

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Detalles Bibliográficos
Autores principales: Bang, Sunjoo, Son, Sangjoon, Kim, Sooyoung, Shin, Hyunjung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483058/
https://www.ncbi.nlm.nih.gov/pubmed/30760209
http://dx.doi.org/10.1186/s12859-019-2638-3